Reaktion #167606

ord-4ee878eb6a984bd6b6f15a0508afa786

Reaktionsgleichung

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
Cc1noc(C)c1B(O)O
3,5-dimethylisoxazol-4-ylboronic acid
→
Cc1noc(C)c1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1
title compound
Cc1noc(C)c1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-[5-(3,5-dimethylisoxazol-4-yl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

Edukte

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
Cc1noc(C)c1B(O)O
3,5-dimethylisoxazol-4-ylboronic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from the product of Example 65A and 3,5-dimethylisoxazol-4-ylboronic acid according to General Method B: LC-MS Method B (ESI+) m/z 325.0 (M+H)+, retention time 1.61 minutes.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846661B2uspto-grants-2014_09