Reaktion #167516

ord-bbcd5cd95dcc48e49829a5a866f02726

Reaktionsgleichung

O=C1OCCC1=CO.[Na]
3-hydroxymethylenedihydrofuran-2-one sodium salt
NCc1ccc(Cl)cc1
4-chlorobenzylamine
O=C1OCCC1=CNCc1ccc(Cl)cc1
3-(4-chlorobenzylamino)methylenedihydrofuran-2-one
Ausbeute 73.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using 3-hydroxymethylenedihydrofuran-2-one sodium salt (10 mmol) and 4-chlorobenzylamine (11 mmol) and proceeding according to the abovementioned method A2, 3-(4-chlorobenzylamino)methylenedihydrofuran-2-one (1.5 g, 73%) is produced in the form of a white powder.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846125B2uspto-grants-2014_09