Reaktion #1674385

Reaktionsgleichung

ortho-phenylenediamine

potassium carbonate

cinnamyl chloride

→

title compound

Ausbeute 89.5%

N-Cinnamyl-1,2-phenylenediamine

Ausbeute 89.5%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionthe reaction mixture was extracted twice with 100 ml and 50 ml of chloroform
2. 2
   Waschenthe extract was washed with a saturated sodium chloride aqueous solution
3. 3
   Trocknendried over magnesium sulfate
4. 4
   Sonstigeevaporated
5. 5
   Sonstigeto remove the solvent under a reduced pressure
6. 6
   Wascheneluted with chloroform

Vorschrift

3.24 g of ortho-phenylenediamine was dissolved in 30 ml of dimithylformaide, to the solution were added 2.07 g of potassium carbonate and 1.52 g of cinnamyl chloride, and the mixture was stirred overnight at a room temperature. After adding 100 ml of water, the reaction mixture was extracted twice with 100 ml and 50 ml of chloroform, and the extract was washed with a saturated sodium chloride aqueous solution, dried over magnesium sulfate and evaporated to remove the solvent under a reduced pressure. The resulting residue was applied to a silica gel column and eluted with chloroform, to obtain 2.0 g of the title compound as light brown crystals.

Quelle