Reaktion #1666477

Reaktionsgleichung

3-(4-cyano-3-nitrobenzoyl)propionic acid

→

3-(3-amino-4-cyanobenzoyl)propionic acid

Lösungsmittel

ammonium hydroxide

ammonium hydroxide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for 15 minutes
2. 2
   EinengenThe filtrate was concentrated

Vorschrift

A solution of 3-(4-cyano-3-nitrobenzoyl)propionic acid in 5N ammonium hydroxide solution was added to a well stirred boiling aqueous solution of ferrous sulphate. The pH was adjusted to 9 with concentrated ammonium hydroxide solution and the mixture was refluxed for 15 minutes. The filtrate was concentrated and neutralised with glacial acetic acid to give 3-(3-amino-4-cyanobenzoyl)propionic acid.

Quelle