Reaktion #165546
ord-abf18c753e23443e860071ffbf9653e8
Reaktionsgleichung
5-amino-2-methylphenol
4-chloro-N-methyl-2-pyridinecarboxamide
→
3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Aufarbeitung
- 1Sonstigehad been synthesized
Vorschrift
Entry 50: According to Method A2, Step 4, 5-amino-2-methylphenol was reacted with 4-chloro-N-methyl-2-pyridinecarboxamide, which had been synthesized according to Method A2, Step 3b, to give 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline to afford the urea.