Reaktion #164092

Reaktionsgleichung

6-heptenoic acid

oxalyl chloride

→

6-Heptenoyl Chloride

Lösungsmittel

CH2Cl2

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenthe reaction mixture was concentrated under reduced pressure
2. 2
   workup.WAITput under high vacuum for 15 min
3. 3
   workup.DISSOLUTIONThe residual yellow oil was dissolved in CH2Cl2 (3 mL)

Vorschrift

To a solution of 6-heptenoic acid (251 μL, 1.85 mmol) in CH2Cl2 (5 mL) at rt was added oxalyl chloride (476 μL, 5.55 mmol) and DMF (1 drop). After stirring for 1 hr, the reaction mixture was concentrated under reduced pressure and put under high vacuum for 15 min. The residual yellow oil was dissolved in CH2Cl2 (3 mL) and used as a stock solution (0.62M) for the subsequent acylation reactions.

Quelle