Reaktion #163332

Reaktionsgleichung

N-[2-(4-bromo-phenyl)-1,1-dimethyl-ethyl]-formamide

HCl

→

2-(4-Bromo-phenyl)-1,1-dimethyl-ethylamine

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturat reflux for 8 h
2. 2
   TemperaturThen heating
3. 3
   workup.STIRRINGthe mixture is stirred at r.t. over night
4. 4
   FiltrationThe precipitate is filtered
5. 5
   Waschenwashed with TBME
6. 6
   Sonstigedried in vacuo

Vorschrift

28.0 g (109 mmol) N-[2-(4-bromo-phenyl)-1,1-dimethyl-ethyl]-formamide (I35) are added to 102 mL water and 101 mL (1218 mmol) conc. HCl and stirred at reflux for 8 h. Then heating is stopped and the mixture is stirred at r.t. over night. The precipitate is filtered, washed with TBME and dried in vacuo.

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