Reaktion #162656

ord-b440f9e1831244a0b541a4df6290b27d

Reaktionsgleichung

O=C([O-])[O-].[K+].[K+]
K2CO3
Oc1cccnc1
3-hydroxypyridine
OCCCl
2-chloroethanol
→
OCCOc1cccnc1
title compound
OCCOc1cccnc1
2-(3-pyridinyloxy)ethanol

Edukte

O=C([O-])[O-].[K+].[K+]
K2CO3
—
D1
Oc1cccnc1
3-hydroxypyridine
OCCCl
2-chloroethanol

Reagenzien

Keine

Lösungsmittel

CN(C)C=O
DMF

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The yield of the title compound according to D1, starting from 3-hydroxypyridine, 2-chloroethanol and K2CO3 in DMF was 19%. The title compound has also been prepared according to EP 0 286 242 A2 starting from methyl [(3-pyridinyl)oxy]acetate.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08835439B2uspto-grants-2014_09