Reaktion #1612178

ord-fd7c53a07e4e4cd6b0060eee8325c3d6

Reaktionsgleichung

O=C(c1ccccc1-c1ccccc1)N1CC2CNCC2C1
Intermediate 17
O=C(c1ccccc1-c1ccccc1)N1CC2CNCC2C1
Biphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone
Cc1cnc(Cl)c(C)n1
2-chloro-3,5-dimethyl-pyrazine
Cc1cnc(N2CC3CN(C(=O)c4ccccc4-c4ccccc4)CC3C2)c(C)n1
title compound
Cc1cnc(N2CC3CN(C(=O)c4ccccc4-c4ccccc4)CC3C2)c(C)n1
2-(Biphenyl-2-ylcarbonyl)-5-(3,5-dimethylpyrazin-2-yl)octahydropyrrolo[3,4-c]pyrrole

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-3,5-dimethyl-pyrazine. MS (ESI) mass calcd. for C25H26N4O, 398.50; m/z found, 399.2 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09079911B2uspto-grants-2015_07