Reaktion #1608776

Reaktionsgleichung

title compound

3-bromo-5-[(ethylsulfanyl)methyl]pyridine

OXONE

acetone

→

title compound

3-bromo-5-[(ethylsulfonyl)methyl]pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationfiltered
2. 2
   Einengenconcentrated under reduced pressure

Vorschrift

To a solution of the title compound from Example 62 Step B (96 mg, 0.41 mmol) in acetone (2.0 mL) was added OXONE® (763 mg, 1.24 mmol). The reaction was stirred at room temperature overnight, then filtered and concentrated under reduced pressure to provide the title compound: LCMS m/z 265.91 [M+2+H]+; 1H NMR (500 MHz, CDCl3) δ 8.72 (s, 1H), 8.53 (s, 1H), 8.00 (s, 1H), 4.19 (s, 2H), 2.96 (q, J=7.4, 2H), 1.43 (t, J=7.4, 3H).

Quelle