Reaktion #1605759

ord-3c0156354b244b05ae3d966ca6bb2f51

Reaktionsgleichung

COc1ccc(C(=O)O)cc1Cl
3-chloro-4-methoxy benzoic acid
COC(=O)[C@H](N)CC(C)C.Cl
D-leucine methyl ester hydrochloride
→
COC(=O)[C@@H](CC(C)C)NC(=O)c1ccc(OC)c(Cl)c1
(R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate

Edukte

COc1ccc(C(=O)O)cc1Cl
3-chloro-4-methoxy benzoic acid
COC(=O)[C@H](N)CC(C)C.Cl
D-leucine methyl ester hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared in a similar manner to example 4 using 3-chloro-4-methoxy benzoic acid and D-leucine methyl ester hydrochloride. MS (M+H, 314.10).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09072313B2uspto-grants-2015_07