Reaktion #160300

ord-4e37f6aadc33490db0e8836e5bbbbf01

Reaktionsgleichung

CCOC(=O)c1ccc(S(=O)(=O)Cl)c(Cl)c1
ethyl 3-chloro-4-(chlorosulfonyl)benzoate
Cn1ccc2cc(CN)cnc21
(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine
Cn1ccc2cc(CN)cnc21
(1-Methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine
→
CCOC(=O)c1ccc(S(=O)(=O)NCc2cnc3c(ccn3C)c2)c(Cl)c1
titled compound
CCOC(=O)c1ccc(S(=O)(=O)NCc2cnc3c(ccn3C)c2)c(Cl)c1
Ethyl 3-chloro-4-(N-((1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methyl)sulfamoyl)benzoate

Edukte

CCOC(=O)c1ccc(S(=O)(=O)Cl)c(Cl)c1
ethyl 3-chloro-4-(chlorosulfonyl)benzoate
Cn1ccc2cc(CN)cnc21
(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine
Cn1ccc2cc(CN)cnc21
(1-Methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The titled compound was prepared according to the procedure described in step-1 of Example 1 from ethyl 3-chloro-4-(chlorosulfonyl)benzoate and (1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)methanamine (step-1 of Example 35).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08829026B2uspto-grants-2014_09