Reaktion #160264

ord-e4cdd6ba81934f72ab04c892c6ceb34d

Reaktionsgleichung

CCOC(=O)c1ccc(S(=O)(=O)Cl)c(Cl)c1
ethyl 3-chloro-4-(chlorosulfonyl)benzoate
CCn1ncc2cc(CN)ccc21
(1-ethyl-1H-indazol-5-yl)methanamine
→
CCOC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(cnn3CC)c2)c(Cl)c1
titled compound
CCOC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(cnn3CC)c2)c(Cl)c1
Ethyl 3-chloro-4-(N-((1-ethyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate

Edukte

CCOC(=O)c1ccc(S(=O)(=O)Cl)c(Cl)c1
ethyl 3-chloro-4-(chlorosulfonyl)benzoate
CCn1ncc2cc(CN)ccc21
(1-ethyl-1H-indazol-5-yl)methanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The titled compound was prepared according to the procedure described in step-1 of Example 1 from ethyl 3-chloro-4-(chlorosulfonyl)benzoate and (1-ethyl-1H-indazol-5-yl)methanamine (step-3 of Example 14).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08829026B2uspto-grants-2014_09