Reaktion #1599831

ord-4fbc95a450724bfda6c1c8d83db532a4

Reaktionsgleichung

Cc1noc(-c2ccc(Br)cc2)c1N
5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine
CC(=O)CCc1cccc(C(F)(F)F)c1
4-(3-trifluoromethyl-phenyl)-butan-2-one
→
Cc1noc(-c2ccc(Br)cc2)c1NC(C)CCc1cccc(C(F)(F)F)c1
[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-[1-methyl-3-(3-trifluoromethyl-phenyl)-propyl]-amine

Edukte

Cc1noc(-c2ccc(Br)cc2)c1N
5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine
CC(=O)CCc1cccc(C(F)(F)F)c1
4-(3-trifluoromethyl-phenyl)-butan-2-one

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared according to the procedure described in Example 8, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 4-(3-trifluoromethyl-phenyl)-butan-2-one.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08217066B2uspto-grants-2012_07