Reaktion #1598349

Reaktionsgleichung

acetic anhydride

compound

2-(7-Methoxy-1-naphthyl)ethanamine hydrochloride

sodium acetate

ethanol

→

title product

N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe reaction mixture is heated
2. 2
   Temperaturto reflux
3. 3
   Sonstigeto return to ambient temperature
4. 4
   Sonstigethe precipitate obtained
5. 5
   Filtrationis filtered off
6. 6
   Waschenwashed with an ethanol/water 35/65 mixture

Vorschrift

In a reactor, 5 g of the compound obtained in Step C and 2 g of sodium acetate are introduced into ethanol. The mixture is stirred, 2.3 g of acetic anhydride are then added, the reaction mixture is heated to reflux and 20 ml of water are added. The reaction mixture is allowed to return to ambient temperature and the precipitate obtained is filtered off and washed with an ethanol/water 35/65 mixture to yield the title product.

Quelle