Reaktion #159723

Reaktionsgleichung

tert-butyl 3-((3-fluorophenoxy)methyl)piperidine-1-carboxylate

methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate

→

title compound

Ausbeute 112.0%

methyl 4-(1-(5-chloro-2-(3-((3-fluorophenoxy)methyl)piperidin-1-yl)nicotinamido)cyclopropyl)benzoate

Ausbeute 112.0%

Reaktionsbedingungen

Vorschrift

The title compound (D203) (97 mg) was prepared according to the experimental procedure described in Description 160 starting from tert-butyl 3-((3-fluorophenoxy)methyl)piperidine-1-carboxylate (D45) (100 mg, 0.323 mmol) and reacting in the second step with methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate (D97) (59 mg, 0.161 mmol).

Quelle