Reaktion #159681

Reaktionsgleichung

5-chloro-2-(3-(3,4-difluorophenoxy)azetidin-1-yl)nicotinic acid

methyl 4-(1-aminocyclopropyl)benzoate

methyl 4-(1-aminocyclopropyl)benzoate hydrochloride

→

title compound ( D155 )

Ausbeute 38.2%

methyl 4-(1-(5-chloro-2-(3-(3,4-difluorophenoxy)azetidin-1-yl)nicotinamido)cyclopropyl)benzoate

Ausbeute 38.2%

Reaktionsbedingungen

Vorschrift

The title compound (D155) (50 mg) was prepared according to the experimental procedure described in Description 144 starting from 5-chloro-2-(3-(3,4-difluorophenoxy)azetidin-1-yl)nicotinic acid (D109) (87 mg, 0.255 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (58.14 mg, 0.255 mmol).

Quelle