Reaktion #159679

Reaktionsgleichung

5-chloro-2-(3-(3-(trifluoromethoxy)phenoxy)azetidin-1-yl)nicotinic acid

methyl 4-(1-aminocyclopropyl)benzoate

methyl 4-(1-aminocyclopropyl)benzoate hydrochloride

→

title compound ( D153 )

Ausbeute 75.7%

methyl 4-(1-(5-chloro-2-(3-(3-(trifluoromethoxy)phenoxy)azetidin-1-yl)nicotinamido)cyclopropyl)benzoate

Ausbeute 75.7%

Reaktionsbedingungen

Vorschrift

The title compound (D153) (120 mg) was prepared according to the experimental procedure described in Description 144 starting from 5-chloro-2-(3-(3-(trifluoromethoxy)phenoxy)azetidin-1-yl)nicotinic acid (D107) (110 mg, 0.282 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (64.43 mg, 0.282 mmol).

Quelle