Reaktion #1596523

Reaktionsgleichung

diphenyliodonium chloride

triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate

water

→

target compound

Ausbeute 96.6%

Diphenyliodonium 2-Pivaloyloxy-1,1-difluoroethanesulfonate

Ausbeute 96.6%

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigereacted at room temperature for 3 hours
2. 2
   SonstigeThe thus-obtained reaction solution
3. 3
   Sonstigewas separated into an organic layer
4. 4
   WaschenThe organic layer was washed five times with 15 mL of water
5. 5
   Einengensubjected to concentration under reduced pressure

Vorschrift

In 10 mL of chloroform, 5 g of a solid of triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate (equivalent to 14.4 mmol) was dissolved by stirring. The resulting solution was admixed with 15 mL of water and 4.78 g (15.1 mmol) of diphenyliodonium chloride, and then, reacted at room temperature for 3 hours. The thus-obtained reaction solution was separated into an organic layer and an aqueous layer. The organic layer was washed five times with 15 mL of water and subjected to concentration under reduced pressure. With this, 7.32 g of the target compound was obtained as a white solid (purity: 90%, yield: 90%).

Quelle