Reaktion #159597

ord-1636a5ec1d944ed6b40c48acc062b179

Reaktionsgleichung

CC(C)(C)OC(=O)N1CCC(O)C1
1-Boc-3-pyrrolidinol
Cc1cccc(O)c1
3-Methylphenol
→
Cc1cccc(OC2CCN(C(=O)OC(C)(C)C)C2)c1
title compound ( D38 )
Ausbeute 107.4%
Cc1cccc(OC2CCN(C(=O)OC(C)(C)C)C2)c1
tert-butyl 3-(m-tolyloxy)pyrrolidine-1-carboxylate
Ausbeute 107.4%

Edukte

CC(C)(C)OC(=O)N1CCC(O)C1
1-Boc-3-pyrrolidinol
Cc1cccc(O)c1
3-Methylphenol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound (D38) (1.59 g) was prepared according to the experimental procedure described in Description 34 starting from 1-Boc-3-pyrrolidinol (1 g, 5.34 mmol) and 3-Methylphenol (0.558 ml, 5.34 mmol).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08828987B2uspto-grants-2014_09