Reaktion #159411

ord-c0f84c2ef1e549adabe5964b9fd7e731

Reaktionsgleichung

COC(=O)c1sc(C(=O)C(C)C)cc1N
3-Amino-5-isobutyrylthiophene-2-carboxylic acid methyl ester
COC(OC)N(C)C
dimethoxymethyldimethylamine
→
COC(=O)c1sc(C(=O)C(C)C)cc1N=CN(C)C
3-(Dimethylaminomethyleneamino)-5-isobutyrylthiophene-2-carboxylic acid methyl ester

Edukte

COC(=O)c1sc(C(=O)C(C)C)cc1N
3-Amino-5-isobutyrylthiophene-2-carboxylic acid methyl ester
COC(OC)N(C)C
dimethoxymethyldimethylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe product with the molecular weight of 382.36 (C13H18N2O3S) was obtained in this way

Vorschrift

3-Amino-5-isobutyrylthiophene-2-carboxylic acid methyl ester and dimethoxymethyldimethylamine were reacted by method B. The product with the molecular weight of 382.36 (C13H18N2O3S) was obtained in this way; MS (ESI): 383 (M+H+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08828991B2uspto-grants-2014_09