Reaktion #159378

Reaktionsgleichung

4-methyl-3-nitrophenol

butyl bromide

sodium carbonate

DMF

→

4-Butoxy-1-methyl-2-nitrobenzene

Lösungsmittel

MTBE

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe cooled reaction solution
2. 2
   Waschenwashed twice each with water and sodium hydroxide solution
3. 3
   SonstigeThe organic phase was dried
4. 4
   Einengenconcentrated
5. 5
   SonstigeThe product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way

Vorschrift

A mixture of 4-methyl-3-nitrophenol (10.0 g), butyl bromide (9.4 g), sodium carbonate (6.9 g) and DMF (50 mL) was heated at 80° C. for 7 hours. The cooled reaction solution was diluted with MTBE and washed twice each with water and sodium hydroxide solution. The organic phase was dried and concentrated. The product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way; MS (ESI): 210 (M+H+).

Quelle