Reaktion #159175

Reaktionsgleichung

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

phenyltrimethylammonium tribromide

→

title compound

2-Bromo-1-(3a,6a-dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe suspension was filtered over CELITE
2. 2
   workup.ADDITIONThe filtrate was diluted with diethyl ether
3. 3
   Waschenwashed with saturated aqueous NaHCO3 and brine
4. 4
   Trocknenthen dried over MgSO4
5. 5
   Filtrationfiltered
6. 6
   Einengenconcentrated

Vorschrift

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone (453 mg, 2.48 mmol) was dissolved in THF (12 mL) and phenyltrimethylammonium tribromide (932 mg, 2.48 mmol) was added. After stirring for 1 h, the suspension was filtered over CELITE. The filtrate was diluted with diethyl ether, then washed with saturated aqueous NaHCO3 and brine then dried over MgSO4, filtered and concentrated to afford the title compound which was carried on without purification.

Quelle