Reaktion #1587683

Reaktionsgleichung

tert-butyl N-tert-butoxycarbonyl-N-[(3-cyclopentylphenyl)methyl]carbamate

hydrogen chloride

→

title compound

(3-Cyclopentylphenyl)methanamine hydrochloride

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe reaction solution was concentrated under reduced pressure, and ether (200 mL)
2. 2
   workup.ADDITIONwas added to the residue
3. 3
   FiltrationThe resulting suspension was filtered
4. 4
   Filtrationthe product collected by filtration
5. 5
   Sonstigewas dried under reduced pressure

Vorschrift

To tert-butyl N-tert-butoxycarbonyl-N-[(3-cyclopentylphenyl)methyl]carbamate (4.70 g), a solution of hydrogen chloride in ethyl acetate (4 M, 50 mL) was added, and the mixture was then stirred at room temperature for 2 hours. The reaction solution was concentrated under reduced pressure, and ether (200 mL) was added to the residue. The resulting suspension was filtered, and the product collected by filtration was dried under reduced pressure to obtain the title compound (2.64 g).

Quelle