Reaktion #158132

Reaktionsgleichung

4,6-dichloro-3-fluoro-2-nitroaniline

2,4-dichloro-5-fluoroaniline

5,7-dichloro-4-fluoro-1H-benzotriazole

→

2-Amino-3-(5,7-dichloro-4-fluoro-2H-benzotriazol-2-yl)-2-methylpropionitrile

5,7-Dichloro-4-fluoro-1H-benzotriazole

Ausbeute 85.0%

4,6-Dichloro-3-fluoro-2-nitroaniline

Reaktionsbedingungen

Vorschrift

2-Amino-3-(5,7-dichloro-4-fluoro-2H-benzotriazol-2-yl)-2-methylpropionitrile [1.3 g, Rf=0.2 (1:1 EA/heptane)] was prepared using a procedure similar to that described in Example 1, part a and b, except starting from 5,7-dichloro-4-fluoro-1H-benzotriazole. 5,7-Dichloro-4-fluoro-1H-benzotriazole (4 g, 85%) was prepared using a procedure similar to that described in Example 11, part a, except starting from 4,6-dichloro-3-fluoro-2-nitroaniline. 4,6-Dichloro-3-fluoro-2-nitroaniline (6.1 g) was prepared using a procedure similar to that described in Example 39, part a, b and c, except starting from 2,4-dichloro-5-fluoroaniline (10 g).

Quelle