Reaktion #157764

Reaktionsgleichung

Dimethylsulfamoyl chloride

triethylamine

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

→

title compound

Ausbeute 57.4%

N,N-Dimethyl-N′-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfuric acid diamide

Ausbeute 57.4%

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe reaction solution was concentrated
2. 2
   Sonstigethe residue was purified by silica gel column chromatography (hexane:ethyl acetate=1:0→2:1)

Vorschrift

Dimethylsulfamoyl chloride (492 mg) and triethylamine (0.95 mL) were added to a solution of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (500 mg) in chloroform (5 mL), and the mixture was stirred at room temperature overnight. The reaction solution was concentrated and the residue was purified by silica gel column chromatography (hexane:ethyl acetate=1:0→2:1) to give the title compound as a pale orange powder (427 mg).

Quelle