Reaktion #1573608

Reaktionsgleichung

hexadecyl bromide

2-methoxypropanol

triethylamine

→

product

Cetyltriethylammonium Bromide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeInto a 2 L round-bottom flask was placed
2. 2
   TemperaturThe flask was heated
3. 3
   Einengenthe contents were concentrated on a Rotavap at 75° C.
4. 4
   workup.ADDITIONTo the residue, methyl tert-butyl ether (800 mL) was added
5. 5
   workup.STIRRINGThe slurry was vigorously stirred by a mechanical stirrer for 12 h
6. 6
   Filtrationfiltered
7. 7
   Waschenwashed with 3 portions (400 mL each) of methyl tert-butyl ether
8. 8
   Sonstigedried in vacuum

Vorschrift

Into a 2 L round-bottom flask was placed hexadecyl bromide (250 g), 2-methoxypropanol (250 mL), and triethylamine (200 mL). The flask was heated without stirring at 75° C. for 96 h and the contents were concentrated on a Rotavap at 75° C. and 20 mbar. To the residue, methyl tert-butyl ether (800 mL) was added. The slurry was vigorously stirred by a mechanical stirrer for 12 h, filtered, washed with 3 portions (400 mL each) of methyl tert-butyl ether, and dried in vacuum to obtain the product as a white solid in nearly quantitative yield.

Quelle