Reaktion #157097

Reaktionsgleichung

4-chloro-3-nitropyridine

(+/−)-3-hydroxypiperidine

triethylamine

→

(+/−)-1-(3-nitropyridin-4-yl)piperidin-3-ol

Lösungsmittel

DMF

Reaktionsbedingungen

Vorschrift

Method 1 of Example 1 was followed using 1 equivalent each of 4-chloro-3-nitropyridine, (+/−)-3-hydroxypiperidine and triethylamine in DMF yielding (+/−)-1-(3-nitropyridin-4-yl)piperidin-3-ol, LCMS (m/z): 224.1 (MH+); LC Rt=1.06 min.

Quelle