Reaktion #156300

Reaktionsgleichung

tert-butyl 4-[3-(pyridin-3-yl)propyl]piperazine-1-carboxylate

hydrogen chloride dioxane

→

1-[3-(pyridin-3-yl)propyl]piperazine trihydrochloride

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated under reduced pressure

Vorschrift

To a solution of 420 mg of tert-butyl 4-[3-(pyridin-3-yl)propyl]piperazine-1-carboxylate in 6 mL of methanol was added 2 mL of a 4 M hydrogen chloride-dioxane solution, followed by stirring at room temperature for 16 hours. The solvent was evaporated under reduced pressure to obtain 395 mg of 1-[3-(pyridin-3-yl)propyl]piperazine trihydrochloride.

Quelle