Reaktion #155893

ord-41bcfca106a847c68415595eaf259f00

Reaktionsgleichung

COc1nn(-c2ccccc2)c2cc(Br)ccc12
6-bromo-3-methoxy-1-phenyl-1H-indazole
c1cc(N2CCNCC2)ccn1
1-pyridin-4-yl-piperazine
Cl
HCl
→
COc1nn(-c2ccccc2)c2cc(N3CCN(c4ccncc4)CC3)ccc12.Cl
title compound
COc1nn(-c2ccccc2)c2cc(N3CCN(c4ccncc4)CC3)ccc12.Cl
3-Methoxy-1-phenyl-6-(4-(pyridin-4-yl)piperazin-1-yl)-1H-indazole hydrochloride

Edukte

COc1nn(-c2ccccc2)c2cc(Br)ccc12
6-bromo-3-methoxy-1-phenyl-1H-indazole
c1cc(N2CCNCC2)ccn1
1-pyridin-4-yl-piperazine
Cl
HCl

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure as described in Example 57 reacting 6-bromo-3-methoxy-1-phenyl-1H-indazole and 1-pyridin-4-yl-piperazine, followed by de-protection with HCl.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08822447B2uspto-grants-2014_09