Reaktion #1552050

Reaktionsgleichung

1,8-octanediamine

triethylamine

furoyl chloride

→

N,N′-(octane-1,8-diyl)bis(furan-2-carboxamide)

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe resulting compound was purified by column chromatography (98:2 DCM:EtOAc)
2. 2
   Sonstigethe product obtained as a white solid (21.5 g/92%)

Vorschrift

The general procedure was carried out using 1,8-octanediamine (10.0 g, 69.3 mmol), triethylamine (14.2 g, 141 mmol), DMAP (0.17 g, 1.35 mmol) and furoyl chloride (19.0 g, 146 mmol). The resulting compound was purified by column chromatography (98:2 DCM:EtOAc), and the product obtained as a white solid (21.5 g/92%).

Quelle