Reaktion #1538485

Reaktionsgleichung

2,3-bishydrazinocarbonyl-5-bromo-7-ethyl-4-hydroxyquinoline

→

title compound

Ausbeute 70.0%

9-Bromo-2,3-dihydro-7-ethyl-10-hydroxypyridazino[4,5-b]quinoline-1,4-dione

Ausbeute 70.0%

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturAfter cooling to room temperature
2. 2
   Filtrationthe reaction mixture was filtered
3. 3
   Waschenthe collected solids washed with acetic acid and air
4. 4
   Sonstigedried

Vorschrift

A stirred mixture of 2,3-bishydrazinocarbonyl-5-bromo-7-ethyl-4-hydroxyquinoline (0.40 g, 1.1 mM) in glacial acetic acid (12 mL) was heated at 81° C. for 1.5 hr. After cooling to room temperature, the reaction mixture was filtered and the collected solids washed with acetic acid and air dried to provide the title compound (0.25 g, 70%) as a light brown solid, mp >400° C.; MS(CI): 336 (M+H). Analysis for C13H10BrN3O3 ·0.13 CH3CO2H Calculated: C, 46.31; H, 3.08; N, 12.21 Found: C, 46.50; H, 3.32; N, 12.19

Quelle