Reaktion #1533421

Reaktionsgleichung

5-(2-chlorophenyl)isoxazole-4-carboxylic acid

2-pyrrolidin-3-yl-pyrazine trihydrochloride

→

title compound

2-(1-{[5-(2-Chlorophenyl)isoxazol-4-yl]carbonyl}pyrrolidin-3-yl)pyrazine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified by preparative HPLC method B

Vorschrift

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 2-pyrrolidin-3-yl-pyrazine trihydrochloride (15.5 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (7.0 mg). Calcd for C18H15ClN4O2: 354.0884, found 354.0885.

Quelle