Reaktion #1532596

Reaktionsgleichung

4-methyl-2-nitro-thiobenzamide

4-Methyl-2-nitro-thiobenzamide

2-bromo-butyraldehyde

2-Bromo-butyraldehyde

→

title compound

Ausbeute 61.0%

5-Ethyl-2-(4-methyl-2-nitro-phenyl)-thiazole

Ausbeute 61.0%

Reaktionsbedingungen

Vorschrift

The procedure described in Example 15-1 was followed, except that 4-methyl-2-nitro-thiobenzamide (56) was used instead of 4-trifluoromethyl-2-nitro-thiobenzamide, and 2-bromo-butyraldehyde (54) was used instead of 1-bromo-3-methyl-butan-2-one, which gave the title compound (60 mg, 61%). LC/MS: (Method I): tR=1.52 min, >95%, m/z (ESI+)=249 (MH+).

Quelle