Reaktion #1528348

ord-e5a41565ce3a43b0b50086be3581fde0

Reaktionsgleichung

N[C@H]1CCCC=C1Cl
(S)-2-chloro-cyclohex-2-enylamine
O=C(O)[C@H](Cc1ccccc1)NN1C(=O)c2ccccc2C1=O
phthalimido-L-phenyalanine
→
NC(=O)CCc1ccccc1
3-phenyl-propionamide

Edukte

N[C@H]1CCCC=C1Cl
(S)-2-chloro-cyclohex-2-enylamine
O=C(O)[C@H](Cc1ccccc1)NN1C(=O)c2ccccc2C1=O
phthalimido-L-phenyalanine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In Scheme A step f, (S)-2-chloro-cyclohex-2-enylamine is reacted with an appropriate phthalimido-L-phenyalanine derivative to give (S)-N-(2-chloro-cyclohex-2-enyl)-2- 2(S)-1,3-dihydro-1,3-dioxo-isoindol-2-yl)-3-phenyl-propionamide.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05502253uspto-grants-1996_03