Reaktion #1519143

Reaktionsgleichung

dihydronaphthalene

N-bromosuccinimide

ether

→

expected compound

trans-2-Bromo-1,2,3,4-tetrahydronaphth-1-ol

Lösungsmittel

water

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONthere are added
2. 2
   Sonstigethe phases are separated
3. 3
   ExtraktionThe aqueous phase is extracted with 200 ml of ether
4. 4
   Waschenthe combined organic phases are then washed with 200 ml of a saturated aqueous solution of sodium chloride
5. 5
   Sonstigedried
6. 6
   Sonstigeevaporated

Vorschrift

To 13.0 g (100 mmol) of dihydronaphthalene, dissolved in a mixture of 100 ml of water and 400 ml of tetrahydrofuran, at ambient temperature, there are added, all at once, 19.6 g (110 mmol) of N-bromosuccinimide and stirring is carried out for 3 hours. There are then added 200 ml of ice-cold water and 200 ml of ether; stirring is carried out and the phases are separated. The aqueous phase is extracted with 200 ml of ether; the combined organic phases are then washed with 200 ml of a saturated aqueous solution of sodium chloride and dried and then evaporated to yield the expected compound.

Quelle