Reaktion #1519138

Reaktionsgleichung

5-bromo-2-hydroxybenzaldehyde

potassium carbonate

4-bromobut-1-ene

acetone

→

4-[5-bromo-2-(but-3-en-1-yloxy)phenyl]-4-hydroxybutan-2-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe reaction mixture is then heated
2. 2
   Temperaturat reflux for 36 hours
3. 3
   Temperaturbefore being cooled
4. 4
   Filtrationfiltered
5. 5
   Sonstigeevaporated to dryness

Vorschrift

To 300 ml of acetone there are added 10 g of 5-bromo-2-hydroxybenzaldehyde (49.7 mmol), 13.7 g of potassium carbonate (99.5 mmol) and 10.1 ml of 4-bromobut-1-ene (99.5 mmol); the reaction mixture is then heated at reflux for 36 hours before being cooled, filtered and evaporated to dryness to yield 4-[5-bromo-2-(but-3-en-1-yloxy)phenyl]-4-hydroxybutan-2-one in the form of an oil.

Quelle