Reaktion #1519132

ord-7f72424fcd7746e7bff83143375ca9e6

Reaktionsgleichung

c1coc([C@@H]2CCCN2)n1
2-(S)-pyrrolidin-2-yl-oxazole
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
→
CCCC[C@@H](C(=O)N1CCC[C@H]1c1ncco1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCC[C@H]1c1ncco1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[2 (S)-oxazol-2-yl-pyrrolidine-1-carbonyl)-heptanoic acid

Edukte

c1coc([C@@H]2CCCN2)n1
2-(S)-pyrrolidin-2-yl-oxazole
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstige(synthesis is described in Procedure E)

Vorschrift

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and 2-(S)-pyrrolidin-2-yl-oxazole A-5 (synthesis is described in Procedure E) according to General Procedure B.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07612059B2uspto-grants-2009_11