Reaktion #1519129

ord-3ed93ec9d8184693989230b7d5e13d59

Reaktionsgleichung

c1ccc(C2CCCN2)cc1
2-phenyl-pyrrolidine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
→
CCCC[C@@H](C(=O)N1CCCC1c1ccccc1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCCC1c1ccccc1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[2 (R/S)-phenyl-pyrrolidine-1-carbonyl)-heptanoic acid

Edukte

c1ccc(C2CCCN2)cc1
2-phenyl-pyrrolidine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid A-5 and commercially available 2-phenyl-pyrrolidine B-5 according to General Procedure B.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07612059B2uspto-grants-2009_11