Reaktion #1509611
ord-0f1820f999644b6f8a786a75578573de
Reaktionsgleichung
3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene
water acetonitrile
ethyl bromoglutarate
→
2-(3,6,9,15-Tetraazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-3-yl)pentanedioic acid diethyl ester
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Temperatur
50°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
10 mg of 3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene (48.5 μmol) are dissolved in a water-acetonitrile mixture (170 μl of acetonitrile and 7 μl of water). After the addition of 10 μl of TEA (1.4 eq), the mixture is heated to 50° C. and then 13 mg of ethyl bromoglutarate (1 eq) are added. The medium is stirred at 50° C. for 18 h.