Reaktion #1508353

Reaktionsgleichung

4-benzyloxybenzonitrile

THF

hydrogen chloride

→

methyl 4-benzyloxybenzimidate hydrochloride

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe precipitate was filtered off
2. 2
   Waschenwashed with diethyl ether
3. 3
   Sonstigedried

Vorschrift

A solution of 560 mg of 4-benzyloxybenzonitrile in 16 ml of THF and 0.2 ml of methanol, cooled to 0° C., was saturated with hydrogen chloride and kept at 4° C. for 16 hours. The precipitate was filtered off, washed with diethyl ether and dried to give 357 mg of methyl 4-benzyloxybenzimidate hydrochloride, m.p. 179°-180° C.

Quelle