Reaktion #1502890

ord-65e39593c25049fb9aaf2b8d7e339214

Reaktionsgleichung

CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1.O
cephalexin monohydrate
O=C([O-])O.[Na+]
sodium bicarbonate
→
CC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1.[Na+]
cephalexin sodium
Ausbeute 95.0%

Edukte

CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1.O
cephalexin monohydrate
O=C([O-])O.[Na+]
sodium bicarbonate

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    FiltrationThe solution were filtered

Vorschrift

25 gms of cephalexin monohydrate was suspended in 75 ml of water. To this under stirring, 5.75 gms of sodium bicarbonate was added. The solution were filtered and lyophilized to afford 24 gms of crystalline cephalexin sodium.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05908929uspto-grants-1999_06