Reaktion #1497448

ord-649af616d5884b75a133b328ae026f90

Reaktionsgleichung

Cl
HCl
CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)c(N)c1
tert.-butyl-N-(3-amino-4-trifluoromethyl-benzyl)carbamate
→
NCc1ccc(C(F)(F)F)c(N)c1
title compound
Ausbeute 99.0%
NCc1ccc(C(F)(F)F)c(N)c1
3-Amino-4-trifluoromethyl-benzylamine
Ausbeute 99.0%

Edukte

Cl
HCl
CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)c(N)c1
tert.-butyl-N-(3-amino-4-trifluoromethyl-benzyl)carbamate

Reagenzien

Keine

Lösungsmittel

C1CCOC1
THF

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from tert.-butyl-N-(3-amino-4-trifluoromethyl-benzyl)carbamate and—6M HCl in THF in analogy to example 2e.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08921405B2uspto-grants-2014_12