Reaktion #1491800

Reaktionsgleichung

tert-butyl 4-[4-(1-amino-1H-pyrrolo[3,2-b]pyridin-6-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

1-(2,6-dichloro-3-fluorophenyl)ethanone

→

N-[1-(2,6-dichloro-3-fluorophenyl)ethyl]-6-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[3,2-b]pyridin-1-amine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe entitled compound was prepared

Vorschrift

The entitled compound was prepared as described in example 27 by condensing tert-butyl 4-[4-(1-amino-1H-pyrrolo[3,2-b]pyridin-6-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate (prepared in example 18:100 mg, 0.26 mmol) with 1-(2,6-dichloro-3-fluorophenyl)ethanone (excess). The reduction of imine and BOC-deprotection were also carried out as described in Example 27.

Quelle