Reaktion #1483137

Reaktionsgleichung

sodium 4-hydroxy-1,1,2,2-tetrafluorobutane-1-sulfonate

4-bromo-3,3,4,4-tetrafluoro-1-butanol

→

4-Hydroxy-1,1,2,2-tetrafluorobutane-1-sulfonic acid

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionwas extracted with methanol (100 mL)
2. 2
   Filtrationfiltered
3. 3
   Sonstigeto give a light brown solution
4. 4
   Sonstigeto flush any remaining sulfonic acid
5. 5
   SonstigeThe volatiles were removed under reduced pressure
6. 6
   Sonstigeto give a dark brown oil

Vorschrift

The solid from above which contained sodium 4-hydroxy-1,1,2,2-tetrafluorobutane-1-sulfonate was extracted with methanol (100 mL) and filtered. The resulting pale yellow solution was passed through a short column (2.5 cm diameter) which was packed with 7.5 cm of Amberlite 120H acid ion exchange resin to give a light brown solution. Additional methanol was used to flush any remaining sulfonic acid. The volatiles were removed under reduced pressure to give a dark brown oil. The yield was 15.453 g, 77% based on starting 4-bromo-3,3,4,4-tetrafluoro-1-butanol.

Quelle