Reaktion #1481713

ord-cad12631360a486a857229d308375479

Reaktionsgleichung

COC(=O)c1ccc(C#C[Se]c2ccc3c(c2)C(C)(C)CC=C3c2ccc(C(C)(C)C)cc2)cc1
methyl 4-[5-(4-tert-butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanylethynyl]benzoate
O.[Li+].[OH-]
lithium hydroxide monohydrate
→
CC(C)(C)c1ccc(C2=CCC(C)(C)c3cc([Se]C#Cc4ccc(C(=O)O)cc4)ccc32)cc1
4-[5-(4-tert-Butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanylethynyl]benzoic acid

Edukte

COC(=O)c1ccc(C#C[Se]c2ccc3c(c2)C(C)(C)CC=C3c2ccc(C(C)(C)C)cc2)cc1
methyl 4-[5-(4-tert-butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanylethynyl]benzoate
O.[Li+].[OH-]
lithium hydroxide monohydrate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigea cream-colored powder is obtained (0.08 g
  2. 2
    Sonstigem.p. =231° C.

Vorschrift

In a manner similar to that of Example 1g, by reacting 0.28 g (0.5 mmol) of methyl 4-[5-(4-tert-butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanylethynyl]benzoate with 0.28 g (6.6 mmol) of lithium hydroxide monohydrate, a cream-colored powder is obtained (0.08 g; yield=30%; m.p. =231° C.).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07348449B2uspto-grants-2008_03