Reaktion #1470425

Reaktionsgleichung

1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

diethanolamine

→

title compound

Ausbeute 29.9%

1-Oxyl-2,2,6,6-tetramethyl-4-{2-hydroxy-3-[di(2-hydroxyethyl)amino]propoxy}piperidine

Ausbeute 29.9%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   ExtraktionThe solution is then extracted with methylene chloride
2. 2
   ExtraktionThe methylene chloride extract
3. 3
   Trocknenis dried over anhydrous magnesium sulfate
4. 4
   Filtrationfilter
5. 5
   Einengenconcentrated
6. 6
   SonstigeThe crude reaction product
7. 7
   Sonstigeis purified by column chromatography

Vorschrift

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

Quelle