Reaktion #1452492

Reaktionsgleichung

4-(4-Fluoro-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester

HCl

→

4-(4-fluoro-benzenesulfonyl)-piperazine hydrochloride salt

Lösungsmittel

methanol

dichloromethane

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeVolatiles were removed in vacuo

Vorschrift

4-(4-Fluoro-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester (937 mg) was dissolved in methanol (10 ml) and dichloromethane (5 ml), 2M HCl in diethyl ether (13.6 ml) was added and the reaction mixture was stirred at room temperature overnight. Volatiles were removed in vacuo to yield 4-(4-fluoro-benzenesulfonyl)-piperazine hydrochloride salt (819 mg).

Quelle