Reaktion #1447111

Reaktionsgleichung

Et3N

1-naphthol

phosphorus oxychloride

→

title compound

1-Naphthyl dichlorophosphate

Lösungsmittel

Et2O

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.WAITthe resulting solution was left
2. 2
   Temperaturto warm to RT overnight
3. 3
   FiltrationThe white slurry was filtered under an inert atmosphere
4. 4
   Sonstigeall volatiles were removed

Vorschrift

To 1-naphthol in Et2O (0.23 M) was added phosphorus oxychloride (1.0 eq.) and the solution was cooled to −78° C. Neat Et3N (1.0 eq) was added and the resulting solution was left to warm to RT overnight. The white slurry was filtered under an inert atmosphere and all volatiles were removed to yield the title compound as a colorless liquid that was used without further purification in the next step. 31P NMR (400 MHz, CDCl3): δ 3.93 ppm.

Quelle