Reaktion #1444331

ord-ea06f75a91ad41f0b4fa82dfc1131267

Reaktionsgleichung

Cc1ccc(S(=O)(=O)N2C(CCCl)CCC2c2ccc(F)cc2)cc1
(2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine
c1nnn[nH]1
1H-tetrazole
→
Cc1ccc(S(=O)(=O)N2C(CCn3cnnn3)CCC2c2ccc(F)cc2)cc1
title compound
Cc1ccc(S(=O)(=O)N2C(CCn3cnnn3)CCC2c2ccc(F)cc2)cc1
(2RS,5SR)-1-{2-[5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethyl}-1H-tetrazole

Edukte

Cc1ccc(S(=O)(=O)N2C(CCCl)CCC2c2ccc(F)cc2)cc1
(2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine
c1nnn[nH]1
1H-tetrazole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound, colorless oil, MS: m/e=416.1 (M+H+), was prepared in accordance with the general method of example 82b from (2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine and 1H-tetrazole.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06589978B2uspto-grants-2003_07